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Suramin drug reduces emergence of drug resistance in mycobacteria: RGCB Study

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The study tested the efficacy of Suramin, a WHO-approved drug used for treating sleeping sickness and river blindness infections. A family of harmful bacteria that causes diseases like TB and leprosy has become increasingly resistant to antibiotics, and the alarming situation warrants novel strategies to control evolution of drug resistance in mycobacteria, says a study by Dr. Krishna Kurthkoti, a scientist and researcher at Rajiv Gandhi Centre for Biotechnology (RGCB).  The study, published in Antimicrobial agents and chemotherapy, reveals that application of antibiotics results in a two-phase killing of bacteria, with a significant part of the population being killed rapidly while a smaller sub-population of bacteria called ‘persister’ endures the antibiotic and persist in the environment for extended periods. The persisters also get killed because they remain susceptible to antibiotics, but the killing rate is much slower. Non-compliance with the duration of antibiotic therapy resul

The Varanasi factor: Will Modi be able to hold his constituency together?

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With UP sailing to its penultimate phase of polling on March 3, Varanasi is seen as the hot bed of the BJP campaign Uttar Pradesh, for the Bharatiya Janata Party, is crucial in terms of the Assembly elections. Unlike in the past few decades, the saffron outfit doesn’t find the going easy when it comes to voter sentiment. Though the party has been making it seen and heard that BJP is going to be the ultimate winner in the state, the reality may not be so. BJP leaders in Delhi know that well. Things have changed in Uttar Pradesh, and the Opposition parties have grown in strength compared to the earlier Assembly election season. The Congress party has been trying to revive its potential as a formidable force, and the Samajwadi Party has brought in more muscle to its existence. These aspects might be seen as a headache by Yogi Adityanath and his mentor Narendra Modi. The Prime Minister had arrived in the Lok Sabha after a mega win from Varanasi in Uttar Pradesh and he holds the state close

Putin act on Ukraine doesn’t have takers at home; Russian public come together against war

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Russian cities have been witnessing thousands of protesters taking to the streets against Putin’s decision for a military operation in Ukraine Even as Russia continued with its military operation in Ukraine, the country has been seeing huge protests against the decision to go to war on the home front itself. Russian cities have been witnessing thousands of protesters taking to the streets against President Vladimir V. Putin’s decision to invade Ukraine. Though the Russian administration is unleashing a severe crackdown against protestors, the spirit of protests against the war I not willing to die down. Putin’s military operation against Ukraine had come in for major criticism from Russians themselves, as they joined the global community in condemning the military action. Ukraine has always been a brotherly nation for the Russians and when the President Putin ordered a full-scale assault, it came about as an act that left them depressed and disappointed. Russian cities witness massive

Mumbai, Pune venues pad up as IPL set for March 26 start

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10 teams to vie with each other for IPL supremacy, bio-bubble in place It’s all set for yet another exciting cricket season, with the Board of Control for Cricket in India (BCCI) zeroing in on a March 26 date for the IPL. The Indian Premier League (IPL) is all geared up to begin on March 26, and will have Mumbai and Pune as the host venues. While the prestigious Wankhede Stadium, Brabourne Stadium and DY Patil Stadium in Mumbai will host as many as 55 matches in this IPL season, the Maharashtra Cricket Association Stadium in Pune will prove to be the venue for the remaining 15 games. IPL bio-bubble in place for smooth tourney The Covid -19 situation is now on the wane, but the risk factor still persists. And so, ensuring a bio bubble for the players and officials is imperative even at this stage. This is seen as a reason for the BCCI deciding against allowing matches in home states of the IPL teams, and settling for a single state as host venue. The BCCI decided so at a virtual meet on

Indian nationals hope against hope as Ukraine scene turns grim; Ukraine dissatisfied over India’s stance

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As Russia begins military operation in Ukraine, Indian nationals have been left in the lurch. Vladimir Putin, the Russian President’s, military operation in Ukraine has begun, and the world is watching with bated breath on whether it would transform itself into a full scale war in Europe. The action, which has thrown global appeal to Russia to the wind, is appalling and, as NATO described it, is “aggression against a sovereign and independent country”. As the military operation sees an escalation, the Indian nationals in Ukraine are left in the lurch. Though the Indian embassy in Ukraine has urged Indian nationals to maintain calm and remain safe wherever they are, the situation looks frightening. The closure of the Ukranian airspace for civilian aircraft has prompted Air India flights to return. The embassy has been repeatedly saying that alternative arrangements are being made for evacuation of Indian nationals. Embassy asks Indian nationals to stay calm Going by a communique that ha

MINI completes 10 years in India, unveils its first all-electric MINI 3-Door Cooper SE

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MINI is celebrating 10 years in India with the launch of the first all-electric car in the compact premium segment. It’s been a decade since the first MINI arrived in the country. And now, with the electric car revolution gaining in prominence, the car maker has brought to Indian shores its first all-electric MINI 3-Door Cooper SE . Being offered as completely built-up unit (CBU), the company saw that all available units were sold out during the pre-launch booking in Q4 2021. MINI India will be delivering the cars to the pre-launch customers from March 2022, earlier than promised. Bookings for the next phase of deliveries will start from March 2022, on the MINI Online Shop . The company has stated that the MINI Electric brings with it the iconic character of MINI along with all the benefits of going electric. Promising zero emissions, it comes across as a combination of sustainable driving and thrilling driving performance. Significantly, the new vehicle is the first series model exclu

LIC looks at stronger digital presence in bid to grow market share

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LIC, gearing up for its IPO, will look at strengthening digital presence in its efforts to halt sliding market share IPO-bound Life Insurance Corporation of India (LIC) has been battling a peculiar problem for the past so many years. The problem may be attributed to its failure in halting the reduction in its market share even as new generation life insurers have been galloping ahead on that front. LIC’s over dependence on physical agents has been seen as contributing to this problem. In a bid to reduce its dependence on agents in the field, LIC is now looking towards a new digital avatar and has lined up measures to strengthen its digital presence. Shifting its stance and banking on more digitalisation aspects, the life insurer would soon line up an entirely new vertical that would stand cemented on a digital platform. This is expected to help in its digital growth and also lure more investors after it goes public on the bourses. Dip in market share prompts LIC digital plan The compan